BioProcess International Poster Preview: Small Scale Protein Purification for Rapid Optimization of Biotherapeutic Protein Production

Leading up to the BioProcess International Event, we'll be highlighting many of the posters you'll be able to find in the hall at the event taking place September 16-19, 2013 in Boston, MA. If you'd like to join us at the event, as a reader of this blog, when you register to join us and mention code BLOG13JP, you'll save 20% off the standard rate!

Poster: Small Scale Protein Purification for Rapid Optimization of Biotherapeutic Protein Production

Presenter: Andrew Barry, PerkinElmer

About: Optimization of expression and purification conditions presents a key challenge towards the development of processes to efficiently produce biotherapeutic proteins. The ability to screen matrices of conditions critical to protein identity, titer, structure, and function requires systems for rapid purification and analysis. Small scale protein purification enables increased sample throughput and reduced purification time, resulting in faster, more efficient optimization for biotherapeutic process development. These advances enable the use and scaling of novel resins through functional dynamic inding capacity testing for ion exchange and affinity chromatography. Here, we will discuss automated purification using three different modalities, each with benefits of loading mass, speed of purification, and flexibility of resin choices and sample throughput.

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