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Leading up to the BioProcess International Event, we'll be highlighting many of the posters you'll be able to find in the hall at the event taking place September 16-19, 2013 in Boston, MA. If you'd like to join us at the event, as a reader of this blog, when you register to join us and mention code BLOG13JP, you'll save 20% off the standard rate! 
Poster: High Throughput Viscosity Measurement for Assessing Biologics FormulationsPresenter: David Yamane, Freeslate
About: Biologic formulations are trending toward higher protein concentrations. High concentration formulations can reach viscosities that are not viable for commercialization. Viscosity is consequently becoming a critical consideration during the assessment of potential formulations. Freeslate has developed the CM Protégé Biologic Formulation Assessment System which has a High Throughput Viscosity Measurement Module that enables viscosity measurement of samples using a volume of 100 microlitre and has a throughput of three minutes per measurement. The system can be used to measure both Newtonian and non-Newtonian fluids. The system has been optimized for the measurement of viscous samples (1 cP to 100 cP) across a temperature range from 4 °C to 40 °C. To evaluate the performance of the High Throughput Viscosity Measurement Module on the CM Protégé Bioformulation Assessment System, Bovine Serum Albumin, multiple concentrations of a monoclonal antibody solution measured at multiple temperatures and 24 different monoclonal antibody (mAb) formulations, were tested. Measurements were fast, ~3 minutes/sample, consumed only 100 microlitre of sample and showed excellent reproducibility.
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