Monday, October 18, 2010

Consortium close to human trials of HIV vaccines

The first human trial of the HIV vaccine candidate designed by Los Alamos National Laboratory researcher Bette Korber is part of an international team of investigators will fight the genetic diversity of the vaccine. Tests on animals have shown early success, and the vaccine is designed to protect against a variety of HIV strands. Read the full press release here.

According to Korber, "HIV's diversity is vast, and the mosaic gene design represents a novel vaccine design to directly tackle HIV diversity in human clinical trials. Based on computational models, mosaic vaccines were predicted to perform better than natural HIV genes; experimental studies in animals, which directly compared mosaic to natural vaccines, supported that prediction. We are excited to test this concept in humans."

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