Showing posts with label Biologic therapeutics. Show all posts
Showing posts with label Biologic therapeutics. Show all posts

Wednesday, July 9, 2014

Delivering Safe, Effective Therapeutics: IIR’s Immunogenicity and Bioassays Conferences


Two events, one goal.

Bring safe and effective therapeutics to the patient faster with IIR’s Immunogenicity and Bioassays conferences. 

The complexity of developing effective biologic therapeutics require adequate analytical methodology to characterize both their physicochemical properties and biological activity. Reducing the risk of triggering unwanted immune responses must be considered early on in drug development. The events focus on the current practice of comprehensive characterization of biotherapeutics from their discovery through all stages of their development.

IIR invites you to join us October 20-22, 2014 in Boston, MA for two co-located events: 15th Annual Immunogenicity for Biotherapeutics and 10th Annual Bioassays and Bioanalytical Method Development.

Download the brochure to find out how to register for one or both events and see for yourself why these are two can't miss events.




Now, you can save $100 on the current rate for each event. Register here with code XP1938BLOG for the Immunogenicity for Biotherapeutics conference.  Register here with code XP1969BLOG for the Bioassays and Bioanalytical Method Development conference. 

Questions? Comments? Reach out at MMadarasz@iirusa.com. 


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Wednesday, July 25, 2012

A Novel Bioluminescent Assay to Measure ADCC & CDC with the use of Automation

Cell Technology, partners of the Bioassays and Bioanalytical Method Development Event this October, recently published a poster about the novel bioluminescent assay titled: A Novel Bioluminescent Assay to Measure ADCC & CDC with the use of Automation.

Highlights of the poster include:
The success of biologic therapeutics has begun to reshape today’s pharmaceutical market. The first and most successful of these antibody therapies, Rituximab (Rituxan®; Roche/Genentech), showed worldwide sales in 2009 of $5.6 billion (GEN News Highlights, 2011). This, among others including Trastuzumab (Herceptin®; Hoffman-La Roche), have shown great promise for treatment of patients with leukemia, lymphomas, breast, and other cancer types due to their specificity and reduced side effects (Zhou, 2007). One of the mechanisms which play a central role in the response to clinical antibody therapy is Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) (Wang, 2008). This involves the response of natural killer (NK) cells to bind to specific antibody-coated target cells, such as CD20 and HER2 expressing cells, to promote the death of the target cell.

Read the full poster here.

Bioassays and Bioanalytical Method Development Conference this October 1-3, 2012 in Berkley, California.  For more information on this event, download the agenda. To join Cell Technology at the event,register today and mention code XP1768BLOG to save 15% off the standard rate.  If you have any questions about the event, email Jennifer Pereira.


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