Date: Tuesday, November 18, 2014Time: 11:00 AM EST
Duration: 15 minutes
Focus: A New Incompressible Protein A Resin to Improve Downstream Productivity in Single Use Applications
Presenter: Dr. Kiran Chodavarapu, Bioprocessing Business Development Manager, W.R. Grace
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Implementation of single use technologies and higher antibody titers upstream have put increasing pressure on downstream processes to improve efficiencies and keep pace with upstream advancements.
There continues to be a lag in the development and adoption of single-use technologies in downstream — particularly in the area of chromatography.
To help achieve the vision of a fully disposable and flexible manufacturing platform that addresses the current bottleneck in downstream processing, a new high-capacity, incompressible Protein A resin has been developed that comes pre-packed in disposable columns. The high capacity silica and bonding chemistry maximize dynamic binding capacity while controlling non-specific protein binding.
About the presenter:
Dr. Kiran Chodavarapu is the Bioprocessing Business Development Manager at W.R. Grace. He leads the commercial and technical development of Grace's bioprocessing products including ProVance® biopurification columns for single campaign use.
Dr. Chodavarapu has a Ph.D. in Chemical Engineering from the University of Massachusetts, Amherst. He joined Grace in 2001 and has extensive R&D experience with zeolite, alumina and silica technologies. During his tenure at Grace, he has led plant start-ups and operational excellence initiatives to drive global manufacturing productivity efforts. He has served in various Engineering, TCS, R&D & Marketing leadership roles within Grace.
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