Antibody Engineering Presentation: Exploiting light chain diversity to create a fully human bispecific IgG platform technology

Over the next few weeks, we'll be looking at some of the best presentations of last year's Antibody Engineering & Therapeutics event.  Today, we feature the presentation Exploiting light chain diversity to create a fully human bispecific IgG platform technology presented by Nicolas Fischer, Ph.D., Head of Research, Novimmune, Switzerland.

During his presentation, Dr. Fischer discussed how kλ-bodies are unmodified fully human bispecific IgGs that contain two different light chains. In contrast to existing engineered formats, kλ-bodies are unique in offering the typical functional and biochemical characteristics of a human antibody. A platform for the isolation of specific and neutralizing antibodies based on light chain diversification as well as a streamlined approach for production and characterization of kλ-bodies will be demonstrated.

Download the full presentation here.

This year, Dr. Fischer will be back to present Exploiting Light Chain Diversity Supports the Development of Multiple Therapeutic Antibody Formats.  For more information on this session and the rest of the program, download the agenda.  If you'd like to join us December 8-12, 2013 in Huntington Beach, California, as a reader of this blog, when you register to join us and mention priority code XD13172BLOGJP and save 20% off the standard rate!

Share this article with your social network, just click below to share now!

Share |